Neovasc Inc. Announces Publication of Positive Tiara Preclinical Data in the Journal JACC: Cardiovascular Interventions

barbara.lempert

- Studies Show Innovative Transcatheter Product to Treat Mitral Regurgitation is Safe, Technically Feasible and Results in a Well-Functioning Mitral Bioprosthesis-
–Sets Stage for First-in-Human Implantations Targeted for Early 2014–
TSX Venture Exchange: NVC
VANCOUVER, Oct. 29, 2013 /CNW/ – (TSXV: NVC) today announced that a review of results from preclinical studies of its ™ valve for the transcatheter treatment of mitral regurgitation has been published in JACC: . The review concludes that implantation of the valve is technically feasible, safe and results in a stable and well-functioning mitral bioprosthesis.
Tiara is a self-expanding mitral bioprosthesis specifically designed to treat mitral valve regurgitation (MR), a serious and poorly served condition that requires development of highly specialized devices to address the complex mitral anatomy.  Mitral regurgitation is often severe and can lead to heart failure and death. Conventional surgical treatments are only appropriate for a small percentage of the estimated four million patients in the US alone.
“This reports on a series of successful Tiara implantations that position us to proceed to the first-in-human Tiara studies we are targeting for early 2014,” noted Alexei Marko, CEO of Neovasc. “ of these results in a prestigious highlights the potential value of Tiara for the growing number of MR patients who cannot be treated surgically. We believe the unique Tiara design may provide important advantages, and we look forward to proceeding to studies in humans next year.”
The preclinical studies included both acute and chronic animal models, as well as human cadavers. Researchers used trans-apical mitral implantation (TAMI), an approach that accesses the mitral valve through the tip (apex) of the left ventricle. Use of TAMI allows the interventional cardiologist easier…Read more

Pharmalive – The Pulse of the Pharmaceutical Industry

Share This Post

Related Articles

Leave a Reply

© 2018 Global Regulatory Science. All rights reserved. Site Admin · Entries RSS · Comments RSS